Dilated cardiomyopathy is a disease of the heart muscle, primarily affecting your heart’s main pumping chamber (left ventricle). The left ventricle becomes enlarged (dilated) and can’t pump blood to your body with as much force as a healthy heart can.
Dilated cardiomyopathy doesn’t necessarily cause symptoms, but for some people the disease is life-threatening. Dilated cardiomyopathy is a common cause of heart failure, the inability of the heart to supply the body’s tissue and organs with enough blood. Dilated cardiomyopathy may also cause irregular heartbeats (arrhythmia), blood clots or sudden death.
Dilated cardiomyopathy may affect people of all ages, including infants and children. Treatments may be available for the underlying cause of dilated cardiomyopathy, or to improve blood flow and reduce symptoms.
What is Duchenne muscular dystrophy?
Duchenne muscular dystrophy (DMD) is a rapidly progressive form of muscular dystrophy that occurs primarily in boys. It is caused by an alteration (mutation) in a gene, called the DMD gene that can be inherited in families in an X-linked recessive fashion, but it often occurs in people from families without a known family history of the condition. Individuals who have DMD have progressive loss of muscle function and weakness, which begins in the lower limbs. The DMD gene is the second largest gene to date, which encodes the muscle protein, dystrophin. Boys with Duchenne muscular dystrophy do not make the dystrophin protein in their muscles.
Muscular dystrophy is a group of genetic diseases in which muscle fibers are unusually susceptible to damage. These damaged muscles become progressively weaker. Most people who have muscular dystrophy will eventually need to use a wheelchair.
There are many different kinds of muscular dystrophy. Symptoms of the most common variety begin in childhood, primarily in boys. Other types of muscular dystrophy don’t surface until adulthood.
People who have muscular dystrophy may have trouble breathing or swallowing. Their limbs may also draw inward and become fixed in that position — a problem called contracture. Some varieties of the disease can also affect the heart and other organs.
While there is no cure for muscular dystrophy, medications and therapy can slow the course of the disease.